One published source for information about the officers and men of the 7th Cav at the time of the Custer Battle is Ronald H. Nichols' "Men With Custer."
According to Nichols, Bobo was born in Franklin County, OH in 1845. However he enlisted at New York City on 23 Dec 1867 and was eventually assigned to Company C, 7th Cav.
He was old enough to have served in the Civil War, but the NPS Civil War Soldiers and Sailors site lists no Edwin L. Bobo in its records.
According to the 7th Cavalry's regimental history, when the regiment was sent to the South, C Company reached its 1st station at Chester, SC on 23 Mar 71. A detachment of the company was sent to Winnsboro, SC in May 71. On 27 Jun 71 the company arrived at its 2nd station at Rutherfordton, NC. Its 3rd station was Lincolnton, NC where it arrived on 13 Mar 72. It's 4th and probably last station in the South was at Charlotte, NC from 31 Oct 72. In Mar 1873 the company assembled with 6 other companies at Memphis for further transport to Dakota. When not in the field the company was stationed at Ft Rice and from 9 Oct 1875 it was stationed at Ft Lincoln. After the LBH it was stationed at Ft Totten
In "The Past Times," a publication of the Fort Abraham Lincoln Foundation, Sep 1998 issue, there was a letter from Robert H. DePriest, Kanipe's great, great, grandson in which he said that Bobo married Missouri Ann Wyskoff on 2 Oct 72. She became a laundress and married Kanipe at Ft Totten in Apr, 1877. According to Nichols Missouri Ann was born in Burke County, NC.
Also according to Nichols, Bobo received a 4 months leave in May 1874 with permission to travel to Europe.
According to Depriest Kanipe travelled by train to Hickory and then walked 10 miles to Lincolnton where he enlisted directly into Company C. This is confirmed by Nichols who said the Kanipe was enlisted by the company commander Capt Verling Hart on 7 Aug 72.
In a letter Mrs Kanipe wrote in 1932 and reprinted in the Newsletter of the L. B. H. A. (I don't know the date) she mentions that because she and her husband were from NC they decided to return there after Kanipe's 2nd enlistment. There was no indication they knew each other before Kanipe joined Company C. There was no indication that Bobo had anything to do with Kanipe's enlistment.
Bobo was killed near Capt Keogh on the eastern slope of Custer Ridge and a good distance from the Last Stand. You can probably take your pick of when and under what circumstances from a great variety of theories.
In "Where Custer Fell" by Brust, Pohanka, and Barnard, there is one photo from a distance of Mrs Kanipe standing among the markers near Keogh's. In another she is standing next to a marker with her husband, the Crow Scout Curly, and another C Company man, Peter Thompson. The photos were apparently taken in 1909.